While it's easy to look at the rise of Sodom and Gomorrah and feel anger in our hearts, we cannot, and must not, tolerate hatred for those who are in bondage to their sin. They've been taken captive by the enemy and don't even know it (2 Timothy 2:24-26).
We need to walk in the Spirit and see that these people are on their way to eternal damnation (John 3:18). We must remember that Jesus died for all sinners (Romans 5:8). We're not given an option of withholding prayer or the Gospel from some because we're angry at what they represent. We're told to go and preach the Truth to all (Matthew 28:18-20).
We also need to stand up for Truth (John 14:6) and be willing to speak it in love, knowing that this is pleasing to the LORD.
We need to show our love for Jesus by praying for sinners and sharing the Good News of salvation through repentance toward God and faith in our Lord Jesus Christ (Acts 20:21; Romans 10:14-15). Don't think you can preach to some and withhold the Truth from others you don't like. That would just reveal a failing within yourself.
Christ died for all; we MUST preach to all, praying that God will deliver some from the grip of the enemy.
Remember the sobering words of Psalm 2:
(1) Why do the heathen rage, and the people imagine a vain thing? (2) The kings of the earth set themselves, and the rulers take counsel together, against the LORD, and against his anointed, saying, (3) Let us break their bands asunder, and cast away their cords from us. (4) He that sitteth in the heavens shall laugh: the Lord shall have them in derision. (5) Then shall he speak unto them in his wrath, and vex them in his sore displeasure. (6) Yet have I set my king upon my holy hill of Zion. (7) I will declare the decree: the LORD hath said unto me, Thou art my Son; this day have I begotten thee. (8) Ask of me, and I shall give thee the heathen for thine inheritance, and the uttermost parts of the earth for thy possession. (9) Thou shalt break them with a rod of iron; thou shalt dash them in pieces like a potter's vessel. (10) Be wise now therefore, O ye kings: be instructed, ye judges of the earth. (11) Serve the LORD with fear, and rejoice with trembling. (12) Kiss the Son, lest he be angry, and ye perish from the way, when his wrath is kindled but a little. Blessed are all they that put their trust in him.